July Newsletter available!

The July Newsletter is now available. You can see this and past newsletters in the DIDB Resource Center. Please note that you must be signed in to access.

Do not hesitate to contact us with comments or suggestions.

DIDB Editorial Team


DIDB Team at the 17th International Conference on Drug-Drug Interactions

The DIDB team will be exhibiting at the 17th International Conference on Drug-Drug Interactions in Seattle on June 30-July 2, 2014, and will contribute to the scientific program with two presentations:

* Critical Review of the 2013-2014 Literature (Dr. Sophie Argon)

* New Molecular Entities Approved by FDA in 2013: Review of In Vitro and In Vivo Data (Dr. Jingjing Yu)

Dr. Ragueneau-Majlessi will be chairing the session entitled “NDA and Literature Update” on June 30th.


e-PKGene Version 2.0 released April 11th!

The DIDB program is pleased to announce the release of e-PKGene Version 2.0.

Please see this detailed description of the new features.

New features include:

  1. A new responsive design that works on phones and tablets.
  2. A set of new quantitative searches:

    • Users are now able to select a combination of factors (compounds, genes, ethnicities) to query for quantitative measurements. Tabular results are provided in % ∆ from the reference population’s measurements and provide both pharmacokinetic (PK) and pharmacodynamic (PD) data.
    • These results can be further refined by filtering individual columns by text or by a numerical range. Columns can also be reordered or hidden from view. With these tools, users can explore the initial result set and refine the data to their needs. The data then can be saved as a spreadsheet.
  3. New design for displaying full citation and NDA information:

    • For each study, all information has been condensed into a single, easy to understand table. Measurement data for the citation/NDA can be viewed in the same manner as the quantitative results query by clicking on the “% ∆ data” link in the description section.
    • At the top of the citation navigation menu, “PK”, “PD”, and “Side Effects” buttons are highlighted only if the citation contains data for it; one click on either button will hide the information which is not of interest.
      needs. The data then can be saved as a spreadsheet.
  4. Updated drug summaries

A new, completely redesigned DIDB is here!

Check out the new DIDB at http://didb.druginteractioninfo.org

What’s new?

  • Whole new look and feel, but don’t get worried, the workflow remains unchanged. You’ll be able to jump right in.
  • New improved autocompletes to find the compound or therapeutic class you want.
  • You can now select a default compound to use in all DIDB queries.
  • New sortable and searchable query result tables.  Give these a try, you’ll like them.
  • A completely new and vastly improved disease section.  Take a look.
  • Oh, and this all works on your tablet or phone… well, if your phone is shiny and new.

If a picture is worth a thousand words, a fully functioning website is worth a thousand pictures. Check it out http://didb.druginteractioninfo.org.

This new version of DIDB went live on November 3rd.

If you have any questions or comments please contact us.

Thank you,

The DIDB technology team


DIDB Team to exhibit at the 10th International ISSX Meeting – Toronto 09/29-10/03, 2013

Please visit the DIDB Team at Booth #602 during this year’s 10th International ISSX Meeting to be held in Toronto, Canada September 29 – October 3, 2013.

Also, please come to the following poster presentation:

  • P168 – Analysis of metabolism and transport drug interaction data in new drug applications approved in 2012 (Mulgaonkar A, Ragueneau-Majlessi I, Chung S, Zhang L, and Zhao P)
  • Tuesday, October 1
  • Poster Viewing: 10:30 – 14:00
  • Presented by Authors: 13:30 – 14:00 (Dr. Ragueneau-Majlessi)

DIDB platform upgrade

The DIDB platform will be upgraded this week-end to run with the latest version of its software. If you experience any issue, please contact us at didbase@uw.edu.


DIDB program releases e-PKGene

The DIDB program has released its pharmacogenetic database, e-PKGene. For more information on e-PKgene please see the e-PKGene User Guide.

Part of the release also includes a new website where DIDB users can easily access both applications with a single login.

First, you need to register and create an individual account. To do so, use your current company login/password for the DIDB, and follow the few steps. When asked to provide your email address, please provide your WORK email.

If you have any questions regarding the release or experience any difficulty creating your new password, please contact us.